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Critical Care Transition Programs on Readmission or Death [Elektronisk resurs] A Systematic Review and Meta-Analysis

Österlind, Jonas (författare)
Gerhardsson, Jakob (författare)
Myrberg, Tomi (författare)
Umeå universitet Medicinska fakulteten (utgivare)
Publicerad: John Wiley & Sons, 2020
Engelska.
Ingår i: Acta Anaesthesiologica Scandinavica. - 0001-5172. ; 64:7, 870-883
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  • Background: Deterioration after ICU discharge may lead to readmission or even death. Interventions (e.g. critical care transition programs) have been developed to improve the clinical handover between the ICU and ward. We conducted a systematic review with meta‐analysis and trial sequential analysis (TSA) according to Cochrane Handbook and Grading of Recommendations, Assessment, Development and Evaluations (GRADE) methodology to assessthe impact of these interventions on readmission and death (PROSPERO, no CRD42019121746). Methods: We searched PubMed/MEDLINE, CINAHL, AMED, PsycINFO and the Cochrane Central Register for Controlled Trials from inception until January 2019. We included historically controlled studies that evaluated critical care transition programs in adults discharged from the ICU. Readmission and in‐hospital mortality were the primary outcomes. Risk of bias, publications bias and the quality of evidence were assessed with the ROBINS‐I tool, funnel plot and GRADE, respectively. Results: Fifteen observational studies were included (11 in meta‐analysis). All studies had at least serious risk of bias. ICU discharge within a critical care transition program modestly reduced the risk of readmission (RR 0.78; 95% CI: 0.64 to 0.96; TSA‐adjusted 95% CI: 0.59 to 1.03) but not in‐hospital mortality (RR 0.82; 95% CI: 0.64 to 1.06; TSA‐adjusted 95% CI: 0.49 to 1.37). There was substantial heterogeneity among studies. TSA indicated lack of firm evidence. The GRADE quality of evidence on outcomes was very low. Conclusions: We found no clear benefit in terms of reducing risk of readmission or death after ICU discharge,however with overall very low certainty of evidence. 

Ämnesord

Medical and Health Sciences  (hsv)
Clinical Medicine  (hsv)
Anesthesiology and Intensive Care  (hsv)
Medicin och hälsovetenskap  (hsv)
Klinisk medicin  (hsv)
Anestesi och intensivvård  (hsv)

Genre

government publication  (marcgt)

Indexterm och SAB-rubrik

critical care
critical care outreach service
critical care transition program
ICU follow-up
ICU liaison nurse
intensive care unit
medical emergency team
mortality
rapid response team
readmission
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