Sex- and age-specific associations between cardiorespiratory fitness, CVD morbidity and all-cause mortality in 266.109 adults [Elektronisk resurs]
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Ekblom Bak, Elin, 1981- (författare)
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Ekblom, Björn, 1938- (författare)
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Söderling, Jonas (författare)
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Börjesson, Mats (författare)
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Blom, Victoria (författare)
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Kallings, Lena, 1969- (författare)
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Hemmingsson, Erik (författare)
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Andersson, Gunnar (författare)
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Wallin, Peter (författare)
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Ekblom, Örjan, 1971- (författare)
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Gymnastik- och idrottshögskolan, GIH Institutionen för idrotts- och hälsovetenskap (utgivare)
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Gymnastik- och idrottshögskolan, GIH Institutionen för idrotts- och hälsovetenskap (utgivare)
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Gymnastik- och idrottshögskolan, GIH Institutionen för idrotts- och hälsovetenskap (utgivare)
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Gymnastik- och idrottshögskolan, GIH Institutionen för idrotts- och hälsovetenskap (utgivare)
- Publicerad: Elsevier, 2019
- Engelska.
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Ingår i: Preventive Medicine. - 0091-7435. ; 127
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- Relaterad länk:
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http://www.gih.se/ (Värdpublikation)
Sammanfattning
Ämnesord
Stäng
- The aim was to investigate sex- and age-specific associations between cardiorespiratory fitness, all-cause and cause-specific mortality, and cardiovascular disease (CVD) morbidity. 266.109 participants (47% women, 18-74 years) free from CVD, participating in occupational health service screenings in 1995-2015 were included. CRF was assessed as estimated maximal oxygen consumption (estVO 2 max) using a submaximal cycle test. Incident cases of first-time CVD event and death from any cause were ascertained through national registers. There were 4244 CVD events and 2750 cases of all-cause mortality during mean 7.6 years follow-up. Male gender, higher age and lower estVO 2 max were associated with higher all-cause mortality and CVD morbidity incidence rates. Risk reductions with increasing estVO 2 max were present in all age-groups of men and women. No obvious levelling off in risk was identified in the total cohort. However, women and older age-groups showed no further reduction in higher aggregated estVO 2 max levels. CVD specific mortality was more associated with estVO 2 max compared to tumor specific mortality. The risk for all-cause mortality and CVD morbidity decreased by 2.3% and 2.6% per increase in 1 ml·min -1 ·kg -1 with no significant sex-differences but more pronounced in the three lower estVO 2 max categories for all-cause mortality (9.1%, 3.8% and 3.3%, respectively). High compared to lower levels of estVO 2 max was not related to a significantly elevated mortality or morbidity. In this large cohort study, CVD morbidity and all-cause mortality were inversely related to estVO 2 max in both men and women of all age-groups. Increasing cardiorespiratory fitness is a clear public health priority.
Ämnesord
- Medical and Health Sciences (hsv)
- Health Sciences (hsv)
- Public Health, Global Health, Social Medicine and Epidemiology (hsv)
- Medicin och hälsovetenskap (hsv)
- Hälsovetenskaper (hsv)
- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv)
- Medicin/Teknik (gih)
- Medicine/Technology (gih)
Genre
- government publication (marcgt)
Indexterm och SAB-rubrik
- Aerobic capacity
- Cancer
- Cardiovascular disease
- Population
- Risk
- VO(2)max
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