Computational Biophysics of Membrane Proteins [Elektronisk resurs] / edited by Carmen Domene.

• 1. Introduction to the Structural Biology of Membrane Proteins / Mary Luckey -- 2. Molecular Dynamics Simulations: Principles and Applications for the Study of Membrane Proteins / Victoria Oakes and Carmen Domene -- 3. Free Energy Calculations for Understanding Membrane Receptors / Andrew Pohorille -- 4. Non-atomistic Simulations of Ion Channels / Claudio Berti and Simone Furini -- 5. Experimental and Computational Approaches to Study Membranes and Lipid–Protein Interactions / Durba Sengupta, G. Aditya Kumar, Xavier Prasanna and Amitabha Chattopadhyay -- 6. Computer Simulation of Ion Channels / Ben Corry -- 7. Computational Characterization of Molecular Mechanisms of Membrane Transporter Function / Noah Trebesch, Josh V. Vermaas and Emad Tajkhorshid -- 8. Computational Studies of Receptors / Maria Musgaard and Philip C. Biggin. 

• Exploring current themes in modern computational and membrane protein biophysics, this book presents a comprehensive account of the fundamental principles underlying different methods and techniques used to describe the intriguing mechanisms by which membrane proteins function. The book discusses the experimental approaches employed to study these proteins, with chapters reviewing recent crucial structural advances that have allowed computational biophysicists to discern how these molecular machines work. The book then explores what computational methods are available to researchers and what these have taught us about three key families of membrane proteins: ion channels, transporters and receptors. The book is ideal for researchers in computational chemistry and computational biophysics. 

Ämnesord

Membrane proteins  (LCSH)

Biophysics  (LCSH)

Computational biology  (LCSH)

Klassifikation

572.696 (DDC)

Ue.04823 (kssb/8 (machine generated))