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Sökning: onr:dm7b5j82blw07vtn > Influence of speech...

  • Doorn, Jan van (författare)
  • 17th International Congress of Parkinson's disease and movement disorders

Influence of speech task and utterance length on the measurement of pitch variability in the speech of Parkinson's disease patients after deep brain stimulation [Elektronisk resurs]

  • E-bokEngelska2013

Förlag, utgivningsår, omfång ...

  • Publicerad:2013

Nummerbeteckningar

  • LIBRIS-ID:dm7b5j82blw07vtn
  • http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-73374uri
  • urn:nbn:se:umu:diva-73374urn

Kompletterande språkuppgifter

  • Språk:engelska

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Anmärkningar

  • Intonation och rytm i talet hos personer med Parkinsons sjukdom - en longitudinell jämförelse mellan sjukdomens effekter och effekter av behandling
  • [Vetenskapsrådet [2011-2294]
  • gratis
  • Parkinson’s disease (PD) affects patients voice characteristics, reducing pitch variability compared to normal controls (1,2). Previous reports have shown an increase in pitch variability due to deep brain stimulation (DBS) of the Subthalamic nucleus (STN) (3). For patients stimulated in caudal zona incerta (cZi), the results indicate no effect on pitch variability in a read speech task{Karlsson:2012jr}. The present study aimed at investigating the effects of speech task (spontaneous or read speech) and the lenght of the utterance on overall measures of pitch variability observed in DBS-treated patients. Ten patients treated with STN-DBS and ten patients treated with cZi-DBS were included in this prospective study. Utterances produced sponatenously and produced during readings of a standard passage were compared in terms of treatment effects in pitch variability due to STN-DBS and cZi-DBS (Stim OFF and Stim ON recordings made 1,5 hour apart, all in Med ON) 6 and 12 months after operation. The results indicate that pitch variability is affected differently by STN-DBS and cZi-DBS depending on speech task and utterance length. In short utterances (<10 words), an increase in pitch variability is observed for both treatment groups and both speech tasks. For longer utterances, however, a more diverse effect of treatment and speech task is observed. The results therefore suggest that spech task and characteristics of thate utterance should be carefully considered when drawing conclusions on the overall effect of DBS on pitch variability. 1. Jiménez-Jiménez FJ, Gamboa J, Nieto A, Guerrero J, Ortí-Pareja M, Molina JA, et al. Acoustic voice analysis in untreated patients with Parkinson's disease. Parkinsonism Relat. Disord. 1997 Apr;3(2):111–6.  2. Holmes RJ, Oates JM, Phyland DJ, Hughes AJ. Voice characteristics in the progression of Parkinsons disease. International Journal of Language & Communication Disorders. 2000;35(3):407–18.  3. Dromey C, Kumar R, Lang AE, Lozano AM. An investigation of the effects of subthalamic nucleus stimulation on acoustic measures of voice. Mov. Disord. 2000;15(6):1132–8.

Ämnesord och genrebeteckningar

Biuppslag (personer, institutioner, konferenser, titlar ...)

  • Karlsson, Fredrik,1975- (författare)
  • Umeå universitetMedicinska fakulteten (utgivare)
  • Umeå universitetHumanistiska fakulteten (utgivare)

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